The connected world creates new potential vulnerabilities for smart advanced cyber-attacks, namely attacks and offender relying on ML/AI and advanced wireless technology integration, to make their attack more effective and less detectable. If an increasing awareness by the users could help to contrast the security issues, it is not sufficient against the new generation of cyber-attacks. In this context, a drastic paradigm shift, putting human-being in the loop for the conception of novel and more effective cyber-security solutions, must be considered. Human-beings have a double role in the cyber-connected world: as potential offender and potential victim. The focus of BEiNG-WISE will be on how these different human-being features can be combined with the advanced technological characteristics, in order to conceive non-conventional, responsible by design, cyber-security solutions accounting for both these factors. In this complex connected system, another fundamental aspect that needs to be accounted to, is the legal one, related to the conception of solutions that can be effectively employed in the real world. Also, legal aspects should be considered at the design stage. The Action relies on cross-domains expertise, ranging from cybersecurity, wireless communication technology, data science, sociology, psychology and law.